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Dehydration sensing in military personnel using Raman spectroscopy

Primary Investigators:
Anita Mahadevan-Jansen
 
Brief Description of Project:
We aim to develop a portable device for noninvasive hydration sensing in high-performing populations who are at elevated risk of dehydration, such as military personnel. This technology will make use of a light-scattering technique called Raman spectroscopy, which provides information about water and other biochemical components in tissue. Existing Raman-based devices are bulky, so they must be scaled down as much as possible while still providing an accurate reading in order to be implemented in a field setting. Once designed and prototyped, the portable device will undergo experimental testing in the lab, and will eventually be used to measure human volunteers before and after exercise.

Desired Qualifications: 
Required:
Proficiency with Matlab
Instrumentation or electronics experience

Preferred:
Basic knowledge of optics and human physiology
Proficiency with SolidWorks or other CAD software 

Nature of Supervision:
Day-to-day laboratory tasks, experimental design, and analysis will be supervised by a senior graduate student and a postdoctoral fellow in my lab. Attendance at weekly meeting with the PI's lab, and project-specific lab groups to discuss troubleshooting and progress is expected. Weekly written updates will be required to be submitted to the PI, followed up with bi-weekly individual meetings directly with the PI. Students will be expected to present research progress to the Biophotonics Center affiliates half way through the program, as well as lead the discussion on the critical review of at least one primary research study at theirs and their advising graduate students choice. Students will responsible for developing and refining an individual development plan (IDP) throughout the summer under guidance from the PI and advising graduate student. Pending research progress, the student may be asked to submit an abstract to present their work at our groups annual international society meeting the following spring and peer reviewed publication.
 
A Brief Research Plan (period is for 10 weeks):
Week 1-2: Learning theory, instrumentation and data processing of Raman spectroscopy. Completing required trainings for lab research and human subjects research, if applicable.
Week 3-8: Design and prototype of device configuration. Experimental testing in optical phantoms, tissues, and/or human subjects. Data analysis and interpretation.
Week 4: Draft for individual development plan (career development) due
Week 6: Biophotonics Center Research Progress Presentation
Week 7: Primary research article presentation
Week 9 : Drafting of conference abstract for submission.
Week 10: Drafting, refining, and delivering final research group presentation 

Number of Open Slots: 1
 
Contact Information:
Name: Anita Mahadevan-Jansen
Department: Biomedical Engineering
Email: anita.mahadevan-jansen@vanderbilt.edu