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Magnetic force microscopy for single molecule and single cell measurements

Primary Investigators:
Matt Lang
 
Brief Description of Project:
This project will involve construction and optimization of magnetic force microscopy for single molecule and single cell measurements. The work will integrate a home built platform with imaging and magnetic forces to apply loads to single molecules and single cells. The project involves a broad range of skills including design of opt-mechanical components, image and video analysis (programming), calibrations, wet-biology at the cell and molecular levels.

Desired Qualifications:
Foundation in chemistry, physics and engineering. Some programming skills. the ability to work with the computer integration of hardware and analysis (Matlab) packages.
 
Nature of Supervision:
The student will work both with graduate students in the lab and directly with Prof. Lang.
 
A Brief Research Plan (period is for 10 weeks):
We are currently in the calibration phase and working on various imaging strategies. We will then move to a few model systems and then integrate the platform with some cell and molecular systems. The strategies learned here will be adapted to the construction of additional instruments.
 
Number of Open Slots: 1
 
Contact Information:
Name: Matt Lang
Department: Chemical and Biomolecular Engineering
Email: matt.lang@vanderbilt.edu