Ph.D., Biomedical Engineering
Georgia Institute of Technology

B.S., Biosystems and Agricultural Engineering
University of Kentucky

Contact Information

5919 Stevenson Center
VU Mailbox: PMB 351631, Nashville, TN 37235-1631 USA

Craig Duvall

Associate Professor of Biomedical Engineering
Director of Graduate Recruiting in Biomedical Engineering

Biomedical Engineering

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Research Focus

Drug delivery, regenerative medicine, RAFT polymerization, stimuli responsive polymers, intracellular delivery of biomacromolecular drugs, on demand drug release, nanocarrier in vivo pharmacokinetics

Current Projects

The Duvall Advanced Therapeutics Laboratory (ATL) specializes in design and application of smart polymer-based technologies for: (1) intracellular delivery of biological drugs such as peptides and nucleic acids, (2) proximity-activated targeting of drugs to sites of inflammation and matrix remodeling, and (3) long-term, “on-demand” drug release from localized depots. These delivery systems are designed to improve the therapeutic index of existing drugs and/or to serve as enabling technologies for manipulation of intracellular targets currently considered to be “undruggable”. To achieve optimal, finely-tuned properties for these varied biomedical applications, polymers are utilized that respond to one or more environmental stimuli including pH, matrix metalloproteinases, reactive oxygen species, and temperature. A sampling of topics currently under investigation in the ATL are RAFT polymerization, tissue regenerative biomaterial scaffolds, nanomedicine and targeted drug delivery, microparticles and biomaterials for locally-controlled drug release. The primary pathological application areas in the lab are increasing longevity of vascular graft function, promoting healing of chronic skin wounds, and developing improved breast cancer therapies. These projects are described in more detail at the following link:

The Duvall lab will be moving in spring 2017 to the new Engineering and Science Building (ESB) where we will be co-localized with other BME faculty working in biomaterials, drug delivery, regenerative medicine, molecular and cellular sensing, and mechanobiology. This collaborative research environment will contain all of the multidisciplinary expertise and equipment necessary to carry out cutting edge research across the full spectrum of synthesis, characterization, and biological testing of regenerative biomaterials and nanomaterials.


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