Professor of Biomedical Engineering
Professor of Radiology and Radiological Sciences
Our research is focused on developing and applying magnetic resonance imaging (MRI) methods to assess tissue structure and function. We take an integrated approach to improving the information that can be extracted from imaging data. Our work includes hardware and pulse sequence design, data analysis, model validation, and applications in clinical and systems neuroscience. Recently, our focus has been on developing better methods for estimating the orientation and microstructural properties of white matter fibers in the central nervous system. These methods can be used to construct the macroscopic wiring diagram of the brain and assess the effects of injury and disease on specific pathways in brain networks.
Nath V, Schilling KG, Remedios S, Bayrak RG, Gao Y, Blaber JA, Huo Y, Landman BA, Anderson AW. “Learning 3D white matter microstructure from 2D histology.” Proc IEEE Int Symp Biomed Imaging. 2019:186-190.
Schilling K, Gao Y, Janve V, Stepniewska I, Landman BA, Anderson AW. “Confirmation of a gyral bias in diffusion MRI fiber tractography.” Hum Brain Mapp 39(3):1449-1466 (2018).
Schilling K, Gao Y, Janve V, Stepniewska I, Landman BA, Anderson AW. “Can increased spatial resolution solve the crossing fiber problem for diffusion MRI?” NMR Biomed 30: 12 (2017).
Anderson AW. “Traveling Internal Plane-wave Synthesis (TIPS) for uniform B1 in high field MRI.” Magn Reson Imaging 36: 187-209 (2017).
Schilling K, Janve V, Gao Y, Stepniewska I, Landman BA, Anderson AW. “Comparison of 3D orientation distribution functions measured with confocal microscopy and diffusion MRI.” Neuroimage 129: 185-97 (2016).
Maitre NL, Slaughter JC, Stark AR, Aschner JL, Anderson AW. “Validation of a brain MRI relaxometry protocol to measure effects of preterm birth at a flexible postnatal age.” BMC Pediatrics. 14:84 (2014).
Jeong HK, Gore JC, Anderson AW. “High-resolution human diffusion tensor imaging using 2-D navigated multishot SENSE EPI at 7 T”, Magn Reson Med 69(3): 793-802 (2013).
Choe AS, Stepniewska I, Colvin DC, Ding Z, Anderson AW. “Validation of Diffusion Tensor MRI in the Central Nervous System using Light Microscopy: Quantitative Comparison of Fiber Properties.” NMR Biomed 25: 900-908 (2012).
Arlinghaus LR, Thornton-Wells TA, Dykens EM, Anderson AW. “Alterations in diffusion properties of white matter in Williams Syndrome.” Magn Reson Imaging 29: 1165-1174 (2011).
Hong X, Arlinghaus LR, Anderson AW. “Spatial Normalization of the Fiber Orientation Distribution Based on High Angular Resolution Diffusion Imaging Data.” Magn Reson Med 61: 1520-1527 (2009).
Anderson AW. “Measurement of fiber orientation distributions using high angular resolution diffusion imaging.” Magn Reson Med 54: 1194-1206 (2005).
Johnson MK, Raye CL, Mitchell KJ, Greene EJ, Anderson AW. “FMRI evidence for an organization of prefrontal cortex by both type of process and type of information.” Cereb Cortex 13: 265-73 (2003).
Anderson AW. “A theoretical analysis of the effects of noise on diffusion tensor imaging.” Mag Res Med 46:1174-1188 (2001).
Gauthier I, Skudlarski P, Gore JC, Anderson AW. “Expertise for cars and birds recruits areas involved in face recognition.” Nature Neuroscience 3, 191-197 (2000).
Anderson AW, Gore JC. “Analysis and Correction of Motion Artifacts in Diffusion Weighted Imaging.” Magn Reson Med 32, 379-387 (1994).