Research Professor of Medicine
Research Professor of Biomedical Engineering
My research interest is to provide hi-fidelity physiological phenotyping of sympathetic and cardio-vagal baroreflex in patients with autonomic dysfunction. I have over 25 years of experience in the physiological assessment of sympathetic function in humans in response to physiological stressors such as tilt table testing, lower body negative pressure, neck suction, and pharmacological testing. I am interested in developing new methods in signal processing of sympathetic neural outflow, spectral analysis of physiological signals, and modeling. My goal is to create tools to improve life quality for patients with autonomic dysfunction.
I combine state-of-the-art techniques for assessment of sympathetic nerve activity and firing properties, multiple methods for measurement of fluid shifts, volume and cardiac output, and specialized analytical methods for characterization of neural innervation and autonomic function.
Dr. med. André Diedrich is a Research Professor of Medicine and Biomedical Engineering. He studied Medicine and Medical Cybernetics at the 2nd Medical Institute in Moscow (Russia) and received his MD in 1985. Dr. Diedrich got his specialization certificate in Pathophysiology. He defended his PhD in Medicine at the Humboldt University in Berlin, Germany in 1991.
Dr. Diedrich was awarded with an external fellowship of the European Space Agency in 1996. He got trained in microneurographic techniques and baroreflex testing by Dr. Dwain
L. Eckberg at Virginia Commonwealth University in Richmond, Virginia from 1996 to 1997.
Dr. Diedrich was member of the International Neurolab Team at the NASA space shuttle mission STS90. He received a fellowship in Clinical Pharmacology at the Vanderbilt University, Nashville Tennessee from 1997 to 2000. He was awarded with the Paul Dudley
White International Scholar for highest ranked abstract submitted from United States at the Joint Meeting of Hypertension and AHA Scientific Sessions in 2018. Dr. Diedrich has two patents in smart health care technology for autonomic failure. Dr. Diedrich is member of American Autonomic Society, Associate editor at the Journal of Clinical Autonomic Research and Frontiers in Autonomic Neuroscience.
Dr. Diedrich major fields are space physiology, cardiovascular research, sympathetic baroreflex, and neuromodulation. He was PI of the Analytical and Phenotyping Core of the Dr. David Robertsonʼs PPG of Autonomic Research from 2007 to 2016 (P01 HL056693).
Dr. Diedrich got funded by NIH to develop a Bionic Baroreflex System for Autonomic Failure (R41 AG019576). He and his international collaborator, Dr. Furlan, received funding from Dysautonomia International for the Vagal Stimulation in Postural Tachycardia Syndrome project in 2019. Currently, he is PI of the NIH funded Clinical Trial “Autonomic Determinants of Postural Tachycardia Syndrome” (Clinical Trials NCT04140721, NCT04050410 / R01HL142583).