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Bret Alvis

Associate Professor of Anesthesiology Critical Care Medicine
Associate Professor of Biomedical Engineering

Biomedical Engineering

Research Focus

Translational investigation of vascular waveforms through deconvolution, processing, and analyzes of patterns within the cardiac component, the respiratory component, and their respective harmonics to various volume and respiratory states


Research Articles

  1. Van De Griend P, Herwaldt L, Alvis BD, DeMartino M, Heilmann K, Doern G, Winokur P, DeSalvo Vonstein D, Diekema D. Community-Associated Methicillin-Resistant Staphylococcus aureus, Iowa, USA. Emerging Infectious Disease 2009 October;15(10) PMID: 19861049 PMCID: 2866377.
  2. Sarkar A, Hendrick RJ, Lathrop RA, Alvis BD, Webster RJIII. Design of a Safer Tracheostomy Tube. Journal of Medical Devices 2015 June;9.
  3. Alvis BD, Hughes CG. Physiology Considerations in Geriatric Patients. Anesthesiology Clinics 2015 September;33(3):447-56. PMID: 26315630 PMCID: PMC4556136.
  4. Alvis BD, King AB, Hester D, Hughes CG, Higgins MS. Randomized Controlled Pilot Trial of the Rigid and Flexing Laryngoscope versus the Fiberoptic Bronchoscope for Intubation of Potentially Difficult Airway. Minerva Anestesiologica 2015 September;81(9):946-50. PMID: 25280140.
  5. Alvis BD, Hester D, Watson D, Higgins M, St Jacques P. Randomized Controlled Trial Comparing the McGrath MAC Video Laryngoscope with the King Vision Video Laryngoscope in Adult Patients. Minerva Anestesiologica 2016 January;82(1):30-5. PMID: 25881731.
  6. Hernando D, Sharma SD, Aliyari Ghasabeh M, Alvis BD, Arora SS, Hamilton G, Pan L, Shaffer JM, Sofue K, Szeverenyi NM, Welch EB, Yuan Q, Bashir MR, Kamel IR, Rice MJ, Sirlin CB, Yokoo T, Reeder SB. Multisite, Multivendor Validation of the Accuracy and Reproducibility of Proton-density Fat-fraction Quantification at 1.5T and 3T Using a Fat-water Phantom. Magnetic Resonance in Medicine 2016 April; PMID: 27080068 PMCID: PMC4835219.
  7. Liang Y, Alvis B, Rice MJ, Shaw AD, Deitte LA, Eagle S. A Near-Field Clutter Artifact Mimicking Pulmonary Thrombus during Transesophageal Echocardiography. Anesthesia & Analgesia 2016 October;123(4):831-833. PMID: 27636573.
  8. King AB, Alvis BD, Hester D, Taylor S, Higgins M. Randomized Trial of a Novel Double Lumen Nasopharyngeal Catheter versus Traditional Nasal Cannula during Deep Sedation Gastrointestinal Procedures. J Clin Anesth 2017 May;38:52-56. PMID: 28372678.
  9. Alvis BD, King AB, Pandharipande PP, Weavind L, Avila K, Leisy PJ, Ajmal M, McHugh M, Keegan KA, Baker DA, Walia AW, Hughes CG. Creation and Execution of a Novel Anesthesia Perioperative Care Service at a Veterans Affairs Hospital. Anesthesia & Analgesia 2017 June; PMID: 28632542.
  10. Hocking KM, Alvis BD, Baudenbacher F, Boyer R, Brophy CM, Beer I, Eagle S. Peripheral Intravenous Analysis (PIVA) of Venous Waveforms for Volume Assessment in Patients Undergoing Haemodialysis. British Journal of Anaesthesia 2017 June;119(6):1135-1140. PMID: 29028929.

        Review Articles

  1. Alvis BD, Keohane AM, Hughes CG. An Update on Current Evidence for Sedation Practices in the Intensive Care Unit. Internal Medicine Review 2016 August;2(5). 
  2. King AB, Alvis BD, McEvoy MD. Enhanced Recovery after Surgery, Perioperative Medicine, and the Perioperative Surgical Home: Current State and Future Implications for Education and Training. Currently Open Anaesthesiol 2016 December;29(6):727-732. PMID: 27652514.
  3. Alvis BD, Hughes CG. ASA Refresher: Perioperative Delirium: making sense of all the confusion. American Association of Anesthesiologists 2017 Refresher Courses in Anesthesiology 2017 November.
  4. Chang D, Leisy PJ, Sobey JH, Reddy SK, Brophy C, Alvis BD, Hocking K, Polcz M. Physiology and clinical utility of the peripheral venous waveform. JRSM Cardiovascular Disease 2020 October;9: PMID: 33194174.

        Case Reports

  1. Alvis BD, Sobey CM. Oral Baclofen Withdrawal Resulting in Progressive Weakness and Sedation Requiring Intensive Care Admission. The Neurohospitalist 2016 March.
  2. Bergman L, Eagle S, Alvis BD. Novel Use of Pulse Oximetry with an Oral Airway and a Disposable Pulse Oximetry Sensor in a Critically Ill Burn Patient during Debridement and Grafting: A Case Report. Jacobs Journal of Anesthesiology and Research 2017 June;4(1):24.


  1. Alvis BD, Huston JH, Lindenfeld J, Hocking KM. Author Response to Imamura and Narang. J Card Fail 2019 November;26(1):96-96. PMID: 31765693.