Dario Englot

Associate Professor of Neurological Surgery
Associate Professor of Radiology and Radiological Sciences
Associate Professor of Biomedical Engineering
Associate Professor of Electrical and Computer Engineering
Associate Professor of Neurology
Director of Functional Neurosurgery

Biomedical Engineering
Electrical and Computer Engineering

Intellectual Neighborhoods

• Biomedical Imaging and Biophotonics
• Surgery and Engineering

Research Focus

My laboratory is interested in brain network analysis in neurological disorders using neuroimaging and electrophysiology, with a particular focus in epilepsy. Knowledge of brain network abnormalities in epilepsy will help us better understand the behavioral and cognitive effects of seizures over time, and may lead to better treatments for epilepsy, including surgical procedures and neuromodulation. Our current projects include human fMRI, DTI, and intracranial EEG studies in epilepsy and other neurological disorders.

Selected Publications:

Full publication list at: https://www.ncbi.nlm.nih.gov/pubmed/?term=englot+d

Paulo DL, Wills KE, Johnson GW, Gonzalez HFJ, Rolston JD, Naftel RP, Reddy SB, Morgan VL, Kang H, Roberson SW, Narasimhan S, Englot DJ (2022) SEEG functional connectivity measures to identify epileptogenic zones: Stability, medication influence, and recording condition. Neurology 98(20):e2060-e2072. https://pubmed.ncbi.nlm.nih.gov/35338075/ 

Johnson GW, Cai LY, Narasimhan S, González HFJ, Wills KE, Morgan VL, Englot DJ (2022) Temporal lobe epilepsy lateralisation and surgical outcome prediction using diffusion imaging. J Neurol Neurosurg Psychiatry 93(6):599-608. https://pubmed.ncbi.nlm.nih.gov/35347079/ 

González HFJ, Narasimhan S, Johnson GW, Wills KE, Haas KF, Konrad PE, Chang C, Morgan VL, Rubinov M, Englot DJ (2021) Role of the nucleus basalis as a key network node in temporal lobe epilepsy. Neurology 96(9):e1334-e1346. https://pubmed.ncbi.nlm.nih.gov/33441453/ 

Narasimhan S, Kundassery KB, Gupta K, Johnson GW, Wills KE, Goodale SE, Haas K, Rolston JD, Naftel RP, Morgan VL, Dawant BM, González HFJ, Englot DJ (2020) Seizure-onset regions demonstrate high inward directed connectivity during resting-state: An SEEG study in focal epilepsy. Epilepsia 61(11):2534-2544. https://pubmed.ncbi.nlm.nih.gov/32944945/ 

González HFJ, Chakravorti S, Goodale SE, Gupta K, Claassen DO, Dawant B, Morgan VL, Englot DJ (2019) Thalamic arousal network disturbances in temporal lobe epilepsy and improvement after surgery. J Neurol Neurosurg Psychiatry 90(10):1109-1116. https://www.ncbi.nlm.nih.gov/pubmed/31123139  

Englot DJ, González HJF, Reynolds BB, Konrad PE, Jacobs ML, Gore, JC, Landman BA, Morgan VL (2018) Relating structural and functional brainstem connectivity to disease measures in epilepsy. Neurology 91(1):e67-e77. https://www.ncbi.nlm.nih.gov/pubmed/29848786

Lab website: https://my.vanderbilt.edu/bien/

Biography

Dario J. Englot, principal investigator of the BIEN lab, is Director of Functional Neurosurgery, and tenured Associate Professor of Neurological Surgery, Neurology, Radiology and Radiological Sciences, Electrical and Computer Engineering, and Biomedical Engineering at Vanderbilt. He received his B.S. from the University of Scranton, and his M.Phil. and Ph.D. in Neuroscience as well as M.D. from Yale University. Prior to joining the faculty at Vanderbilt, he completed neurosurgery residency at the University of California, San Francisco, and a clinical and research fellowship at Vanderbilt. He may accept graduate students in Electrical and Computer Engineering, Biomedical Engineering, Neuroscience, and other graduate programs at Vanderbilt.