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Frank Block

Adjoint Assistant Professor of Biomedical Engineering

Biomedical Engineering

Research Focus


    1. Miller DR, Schaffer DK, Neely MD, McClain ES, Travis AR, Block FE 3rd, McKenzie JR, Werner EM, Armstrong L, Markov DA, Bowman AB, Ess KC, Cliffel DE, Wikswo JP. A bistable, multiport valve enables microformulators creating microclinical analyzers that reveal aberrant glutamate metabolism in astrocytes derived from a tuberous sclerosis patient. Sensors and Actuators B: Chemical. Volume 341, 2021. 129972, ISSN 0925-4005,
    2. Block FE 3rd, Waheed S, Lee  T-H J. Electrosurgical and Electrocautery Device Failures and Best Reporting Practices. Journal of Clinical Engineering: 1/3 2019. Volume 44, Issue 1, p 17-23 doi: 10.1097/JCE.0000000000000311
    3. Block FE 3rd, Ortega RA, Brown CW Jr. Failure Mechanisms of Polymeric Medical Devices. Journal of Clinical Engineering: 10/12 2018. Volume 43, Issue 4, p 187-193 doi: 10.1097/JCE.0000000000000299
    4. Block FE 3rd, Kuo JY. Lessons Learned From Safety Engineering Case Studies Applied to Medical Devices. Journal of Clinical Engineering: 7/9 2018. Volume 43, Issue 3, p 111-115 doi: 10.1097/JCE.0000000000000281
    5. Block FE 3rd, Azizi J, Markwell S. Case Studies and Considerations for Combating the Diversion of Infusion Drugs. Journal of Clinical Engineering: 1/3 2018. Volume 43, Issue 1, p 18-21 doi: 10.1097/JCE.0000000000000249
    6. Block FE 3rd. Examining Root Causes of Medical Device Alarm System Failures Using Reports from Food and Drug Administration’s Medical Product Safety Network (MedSun). Journal of Clinical Engineering: 10/12 2017. Volume 42, Issue 4, p 194-199 doi: 10.1097/JCE.0000000000000248
    7. Block FE 3rd. The Role of Forensic Engineering Investigations in Medical Device Reports. Journal of Clinical Engineering: 4/6 2017. Volume 42, Issue 2, p 85-88 doi: 10.1097/JCE.0000000000000208
    8. Block FE 3rd, Block FE Jr; Understanding Caregiver Workflows: A Proposal for Alarm Condition Priorities. Biomed Instrum Technol 1 April 2016; 50 (2): 114–116. doi: 
    9. Block FE 3rd, Block FE Jr; Decreasing False Alarms by Obtaining the Best Signal and Minimizing Artifact from Physiological Sensors. Biomed Instrum Technol 1 November 2015; 49 (6): 423–431. doi: 
    10. Alcendor DJ, Block FE 3rd, Cliffel DE, Daniels JS, Ellacott KL, Goodwin CR, Hofmeister LH, Li D, Markov DA, May JC, McCawley LJ, McLaughlin B, McLean JA, Niswender KD, Pensabene V, Seale KT, Sherrod SD, Sung HJ, Tabb DL, Webb DJ, Wikswo JP. Neurovascular unit on a chip: implications for translational applications. Stem Cell Res Ther. 2013;4 Suppl 1(Suppl 1):S18. doi: 10.1186/scrt379. Epub 2013 Dec 20. PMID: 24564885; PMCID: PMC4029462.
    11. Wikswo JP, Block FE 3rd, Cliffel DE, Goodwin CR, Marasco CC, Markov DA, McLean DL, McLean JA, McKenzie JR, Reiserer RS, Samson PC, Schaffer DK, Seale KT, Sherrod SD. Engineering challenges for instrumenting and controlling integrated organ-on-chip systems. IEEE Trans Biomed Eng. 2013 Mar;60(3):682-90. doi: 10.1109/TBME.2013.2244891. Epub 2013 Feb 1. PMID: 23380852; PMCID: PMC3696887.
    12. Chaurey V, Block FE 3rd, Su Y-H, Chiang P-C , Botchwey E, Chou C-F, Swami NS, Nanofiber size-dependent sensitivity of fibroblast directionality to the methodology for scaffold alignment, Acta Biomaterialia, Volume 8, Issue 11, 2012, Pages 3982-3990, ISSN 1742-7061,