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Jamey Young

Professor of Chemical and Biomolecular Engineering
Associate Professor of Molecular Physiology and Biophysics
Director of Graduate Studies in Chemical Engineering

Chemical and Biomolecular Engineering

Intellectual Neighborhoods

Research Focus

Metabolic engineering; systems biology; diabetes, obesity and metabolic disorders; tumor metabolism; autotrophic metabolism; cell culture engineering

Selected Publications:

  1. C. C. Hughey, F. D. James, D. P. Bracy, E. P. Donahue, J. D. Young, B. Viollet, M. Foretz, D. H. Wasserman. Loss of hepatic AMP-activated protein kinase impedes the rate of glycogenolysis but not gluconeogenic fluxes in exercising mice. Journal of Biological Chemistry 292: 20125–20140, 2017.
  2. B. Faubert, K. Y. Li, L. Cai, C. T. Hensley, J. Kim, L. G. Zacharias, C. Yang, Q. N. Do, S. Doucette, D. Burguete, H. Li, G. Huet, Q. Yuan, T. Wigal, Y. Butt, M. Ni, J. Torrealba, D. Oliver, R. E. Lenkinski, C. R. Malloy, J. W. Wachsmann, J. D. Young, K. Kernstine, R. J. DeBerardinis*. Lactate metabolism in human lung tumors. Cell 171:358–371.e9, 2017.
  3. N. Templeton, K. D. Smith, A. G. McAtee-Pereira, H. Dorai, M. J. Betenbaugh, S. E. Lang, J. D. Young*. Application of 13C flux analysis to identify high-productivity CHO metabolic phenotypes. Metabolic Engineering 43:218–225, 2017.
  4. L. J. Jazmin, Y. Xu, Y. E. Cheah, A. O. Adebiyi, C. H. Johnson, J. D. Young*. Isotopically nonstationary 13C flux analysis of cyanobacterial isobutyraldehyde production. Metabolic Engineering 42:9–18, 2017.
  5. A. K. Leamy, C. M. Hasenour, R. A. Egnatchik, I. A. Trenary, C. Yao, G. J. Patti, M. Shiota, J. D. Young*. Knockdown of triglyceride synthesis does not enhance palmitate lipotoxicity or prevent oleate-mediated rescue in rat hepatocytes. BBA–Molecular and Cell Biology of Lipids 1861:1005–1014, 2016.
  6. Y. M. Whang, S. I. Park, I. A. Trenary, R. A. Egnatchik, J. P. Fessel, J. Kaufman, D. P. Carbone, J.D. Young*. LKB1 deficiency enhances sensitivity to energetic stress induced by erlotinib treatment in non-small cell lung cancer (NSCLC) cells. Oncogene 35:856–866, 2016.