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Karen Joos

Ellis Family Professor of Ophthalmology and Visual Sciences
Professor of Biomedical Engineering

Biomedical Engineering

Intellectual Neighborhoods

Research Focus

Applications of optical techniques for ophthalmic surgery. Primary research areas use of optical coherence tomography.

Selected Publications

Gurdita A, Tan B, Joos KM, Bizheva K, Choh V. Pigmented and albino rats differ in their responses to moderate, acute and reversible intraocular pressure elevation. Doc Ophthalmol. 2017 Apr 7. doi: 10.1007/s10633-017-9586-x. [Epub ahead of print] PMID: 28389912.

Choh V, Gurdita A, Tan B, Feng Y, Bizheva K, McCulloch DL, Joos KM. Isoflurane and ketamine:xylazine differentially affect intraocular pressure-associated scotopic threshold responses in Sprague-Dawley rats. Doc Ophthalmol. 2017;135(2):121-132. doi: 10.1007/s10633-017-9597-7. PMID: 28638951.

Del Giudice G, Wang L, Shen JH, Joos K, Simaan N. Continuum Robots for Multi-Scale Motion: Micro-Scale Motion through Equilibrium Modulation. Proceedings of the 2017 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS 2017). Sept 2017, doi: 10.1109/IROS.2017.8206074.

Tan B, Gurdita A, Choh V, Joos K, Prasad R, Bizheva K. Morphological and functional changes in the rat retina associated with 2 months of intermittent moderate intraocular pressure elevation. Scientific Reports. 2018; 8:7727 (1-11) . doi:10.1038/, PMID: 29769654.

Umfress A, Mawn L, Joos K. Short-term Optic Disc Cupping Reversal in a Patient with Mild Juvenile Open-angle Glaucoma Due to Early Idiopathic Intracranial Hypertension. Journal of Glaucoma, 2019;28:e53-e57.

Del Giudice, G, Shen JH, Joos K, Simaan N. Feasibility of Volumetric OCT Imaging using Continuum Robots with Equilibrium Modulation, In Deligianni F, Dagnino G, Yang GZ (Eds.), Proceedings of the 12th Hamlyn Symposium on Medical Robotics, June 2019.

Grossman AL, Javitt MJ, Moster SJ, Grajewski AL , Pediatric Glaucoma Subcommittee of the American Glaucoma Society (Beck AD, Blieden LS, Bitrian E, Chang TC, Freedman SF, Hodapp E, Joos KM, Reiser BJ, Tanna AP) American Glaucoma Society position statement on cannabinoid use in pediatric glaucoma patients. Ophthalmology Glaucoma. 2019;2:365-366.

Patel SN, Kim SJ, Lalezary M, Shah R, Kuchtey RW, Joos KM, Kammer JA, Cherney EF. Three-Year Findings on Intraocular Pressure Changes in The Prospective Retinal and Optic Nerve Vitrectomy Evaluation (PROVE) Study. Ophthalmic Surg Lasers Imaging Retina. 2019;50(6):371-376. doi: 10.3928/23258160-20190605-05. PMID: 31233154.

Morgan TM, Colazo JM, Duncan L, Hamid R, Joos KM. Two cases of oculofaciocardiodental (OFCD) syndrome due to X-linked BCOR mutations presenting with infantile hemangiomas: phenotypic overlap with PHACE syndrome, Case Reports in Genetics. 2019 Dec 28;2019:9382640. doi: 10.1155/2019/9382640. eCollection 2019. PMID: 31956451

Papadopoulos M, Vanner EA, Grajewski A, and ISOCG CGRN Study Group [Arijit Mithra, Manju Pillai, Swati Upadhyaya, Ganesh Venkataraman (Aravind Eye Hospital, India); Ta Chen Peter Chang, Alana Grajewski, Elizabeth Hodapp (Bascom Palmer Eye Institute, USA); Velota Sung (Birmingham and Midland Eye Centre, UK commenced 6/8/13); Orna Geyer, Alvit Wolf (Carmel Medical Center, Israel commenced 6/3/14); Ellen Mitchell, Ken Nischal (Children's Hospital of Pittsburgh, USA); Sharon Freedman (Duke Eye Center, USA); Allen Beck, Annette Giangiacomo (Emory Eye Center, USA), Anne Coleman (Jules Stein Eye Institute, USA); Arif Khan (King Khaled Eye Specialist Hospital, Saudi Arabia); Anil Mandal, Sirisha Senthil (LV Prasad Eye Institute, India); John Brookes, Peng Tee Khaw, Maria Papadopoulos (Moorfields Eye Hospital, UK); Jocelyn Chua, Ching Lin Ho (Singapore National Eye Center, Singapore); James Brandt (UC Davis Eye Center, USA); Vera Essuman (Korle-Bu Teaching Hospital, Ghana commenced 12/12/13); Ray Areaux, Elena Bitrian, Alana Grajewski (University of Minnesota, USA); Franz Grehn, Thomas Klink (University Hospital Würzburg, Germany); Karen Joos (Vanderbilt Eye Institute, USA)]. International Study of Childhood Glaucoma (ISOCG), Ophthalmology Glaucoma. 2020;3(2):145-157. epub jan 2, 2020 DOI:

Umfress AC, Mawn LA, Joos KM, Donahue SP, Christine C. Surgical management of bilateral epibulbar dermoid cysts with autologous oral mucous membrane transplantation, American Journal of Ophthalmology Case Reports. 2020;20:100982. doi: 10.1016/j.ajoc.2020.100982. eCollection. PMID: 33195879.

Del Giudice G, Orekhov AL, Shen J, Joos KM, Simaan N. Investigation of Micro-motion Kinematics of Continuum Robots for Volumetric OCT and OCT-guided Visual Servoing. IEEE/ASME Transactions on Mechatronics, 2021 Oct;26(5):2604-2615. doi: 10.1109/tmech.2020.3043438. PMID: 34658616 PMCID: PMC8519402

Ahronovich EZ, Simaan N, Joos KM. A review of robotic and OCT-aided systems for vitreoretinal surgery. Adv Ther. 2021 Apr 3. doi: 10.1007/s12325-021-01692-z. Online ahead of print.   PMID: 33813718   Invited Review to Joos KM.

Shibao C, Joos K, Phillips JA 3rd, Cogan J, Newman JH, Hamid R, Meiler J, Capra J, Sheehan J, Vetrini F, Yang Y, Black B, Diedrich A, Roberston D, Biaggioni I. Familial Autonomic Ganglionopathy Caused by Rare CHRNA3 Genetic Variants. Neurology. 2021 May 4:10.1212/WNL.0000000000012143. doi: 10.1212/WNL.0000000000012143. Online ahead of print. PMID: 33947782.