Assistant Professor of Chemical and Biomolecular Engineering
- Nano Science and Technology
- Energy and Natural Resources
- Biomedical Imaging and Biophotonics
- Regenerative Medicine
My research group focuses on nanomedicine and nanophotonics. We design nanomaterials that can be activated with light (and other stimuli such as heat, pH etc.) and utilize them for biomedical applications. Current projects in my group include (1) imaging immunomarkers and response to immunotherapies, (2) metabolic imaging with Raman spectroscopy for high throughput drug screening, (3) examine how the mechanomolecular properties of nanomaterials impact their behavior in vitro and in vivo, and (4) combinatorial photothermal immunotherapies to induce antitumor immunity.
Please see our website for more details https://my.vanderbilt.edu/bardhanlab/
Y-C. Ou, X. Wen, C. A. Johnson, M. N. Tantawy, E. P. Paul, J. N. Bateman, D. Shae, J. A. Webb, R. C. DeLapp, K. L. Boyd, M. Rafat, J. T. Wilson, A. Richmond, A. Mahadevan-Jansen, T. E. Peterson, J. M. Balko, A. E. Vilgelm, R. Bardhan*, “Multimodal Multiplexed Immunoimaging with Gold Nanostars for Detection of Immunomarkers and to Monitor Response to Immunotherapies”, under review
Y-C. Ou, J. A. Webb, C. M. O’Brien, I. Pence, E. C. Lin, E. P. Paul, D. Cole, S-H. Ou, M. Lapierre-Landry, E. S. Lippman, A. Mahadevan-Jansen, and R. Bardhan*, “Diagnosis of Immunomarkers in vivo via Multiplexed Surface Enhanced Raman Spectroscopy with Gold Nanostars “, Nanoscale, 2018, 10, 13092-13105
J. A. Webb#, Y-C. Ou#, S. Faley, E. P. Paul, J. P. Hittinger, C. C. Cutright, E. C. Lin, L. M. Bellan, and R. Bardhan*, “Theranostic Gold Nanoantennas for Simultaneous Multiplexed Raman Imaging of Immunomarkers and Photothermal Therapy”, ACS Omega, 2017, 2, 3583–3594. (# equal contributing first author).
Y-C. Ou, J. A. Webb, S. Faley, D. Shae, E. M. Talbert, S. Lin, C. C. Cutright, J. T. Wilson, L. M. Bellan, and R. Bardhan*, “Gold Nanoantenna Mediated Photothermal Drug Delivery from Thermosensitive Liposomes in Breast Cancer”, ACS Omega, 2016, 1, 234–243
J. A. Webb, W. R. Erwin, H. F. Zarick, J. Aufrecht, H. Manning, M. J. Lang, C. L. Pint, R. Bardhan*, “Geometry Dependent Plasmonic Tunability and Photothermal Characteristics of Multibranched Gold Nanoantennas”, J. Physical Chemistry C, 2014, 118, 3696-3707
J. A. Webb, and R. Bardhan*, “Emerging Advances in Nanomedicine with Engineered Gold Nanostructures” Nanoscale, 2014, 6, 2502-2530
J. A. Webb, J. Aufrecht, C. Hungerford, and R. Bardhan*, “Ultrasensitive Analyte Detection with Plasmonic Paper Dipsticks and Swabs Integrated with Branched Nanoantennas”, J. Materials Chemistry C, 2014, 2, 10446 – 10454
R. Bardhan, L. O. Hedges, C. L. Pint, A. Javey, S. Whitelam, J. J. Urban, “Uncovering the intrinsic size-dependence of hydriding phase transformations in nanocrystals” Nature Materials, 2013, 12, 905-912