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‘NIH’

$1.9 million NIH project to investigate effects of shear stress on cancer cells

Sep. 9, 2021—A biomedical engineering professor has received a $1.9 million NIH grant to investigate the effects of mechanical stimuli such as shear stress on the behavior of cancer cells in blood flow. J. Lawrence Wilson Professor Mike King and his research group will develop the devices for the study as well as new cell lines to...

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Research Snapshot: Exosuit concept developed at Vanderbilt peeks at the future of wearable tech

Mar. 25, 2021—The idea Karl Zelik (Vanderbilt University) Erik Lamers (Vanderbilt University) Karl E. Zelik, assistant professor of mechanical engineering, and recent Ph.D. graduate Erik P. Lamers revealed a new exosuit designed to bring back relief to workers who have been under high strain throughout the pandemic, including last-mile delivery drivers and essential workers. The suit can...

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New $2 million NIH grant advances less invasive procedure for TLE

Feb. 16, 2021—A Vanderbilt research team has received a $2 million National Institutes of Health grant to further develop a needle-size robotic surgery system with real-time MRI guidance for drug resistant temporal lobe epilepsy (TLE). Such a procedure has the potential to reduce or eliminate seizures using a minimally invasive approach over the current standard of care,...

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Drug development under way with discovery of how to treat heart attack

Feb. 16, 2021—Vanderbilt researchers have identified the protein receptor in specialized heart cells that, when removed, preserves cardiac function after a heart attack. This discovery has significant implications for survival after a heart attack, with a promising therapeutic development now underway at the Warren Center for Neuroscience Drug Discovery. The research was led by David Merryman, a...

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Imaging brain’s white matter is predictive “biomarker” for Alzheimer’s disease progression

Nov. 20, 2020—Measuring changes in functional connectivity of the brain’s white matter, which is made up of nerve fibers and their protective myelin coating, can predict Alzheimer’s disease progression, researchers in the Vanderbilt University Institute of Imaging Science have found. Previous studies have correlated variations in blood oxygenation level dependent (BOLD) signals detected by functional magnetic resonance...

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Team receives $4 million NIH grant for rapid test of COVID-19, other respiratory infections

Oct. 13, 2020—Twice in 2019, Nick Adams and his colleagues applied for federal grant money to develop a rapid, precise, in-office test for respiratory infections. This test would skip the time-consuming and expensive steps of purifying the samples for testing or sending them to a lab. Doctors and their patients would not have to wait days, sometimes...

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Team’s sustained work in T-cell immune response awarded P01 grant totaling $11 million

Oct. 4, 2020—For more than a decade Matt Lang and collaborators across the U.S. have worked to recreate key components of T-cells and how they know when to start fighting disease. Conventional wisdom suggested that T-cells formed regular, force-free bonds with infected cells, and in doing so caused the chain reaction of immune response. The team slowly...

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Grissom awarded $1.4 million NIH grant to develop smaller, quieter MRI system

Sep. 1, 2020—Vanderbilt engineers have received a $1.4 million NIH grant to work toward a compact, silent, less expensive and potentially portable MRI device. The team, led by William Grissom, associate professor of biomedical engineering, will develop new hardware, including low-field radio frequency transmission coils and amplifiers, and software that will together translate signals measured from the...

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