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‘Regenerative Medicine’

Biomedical engineers demonstrate potential for first clinically successful osteoarthritis drug

Oct. 19, 2021—Vanderbilt biomedical engineers have demonstrated the potential for the first clinically available osteoarthritis drug that interrupts the disease process rather than solely managing the pain it causes. The group used “packages” of engineered nanoparticles to sustainably deliver a type of RNA to the cells in the joint over time after treatment. With this technique, a...

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NIH backs team’s sustained work in T-cell immune response with $11 million P01 grant

Oct. 1, 2020—REGENERATIVE MEDICINE Parsing T-cell activation is precursor to manipulating immune response to better fight diseases For more than a decade Matt Lang and collaborators across the U.S. have worked to recreate key components of T-cells and how they know when to start fighting disease. Conventional wisdom suggested that T-cells formed regular, force-free bonds with infected...

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A new look at what drives metastasis

Oct. 1, 2020—A bold engineering approach to sort breast cancer cells based on their behavior first has produced compelling data that show less migratory cells create more metastases, contradicting the prevailing hypothesis on how cancer spreads. Preliminary discoveries by Cynthia Reinhart-King, Cornelius Vanderbilt Professor of Engineering, have led to surprising results. The ability of cells to move...

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Tissue engineering expert to deliver Hall Lecture on lessons from use of biomaterials in surgery

Nov. 6, 2019—An expert in tissue engineering who recently received the prestigious NIH Director’s Pioneer Award will deliver a public talk Nov. 18 about lessons learned from biomaterials used in orthopedics and plastic surgery. Jennifer Elisseeff is the fall 2019 speaker in The John R. and Donna S. Hall Engineering Lecture Series. Elisseeff is the Morton Goldberg...

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Engineer uses cotton candy to build artificial blood vessels

Apr. 1, 2015—Vanderbilt University mechanical engineer Leon Bellan is working to create artificial human capillary blood vessels using cotton candy and gelatin. His goal is for researchers to use these man-made capillaries to help keep artificial organs and other tissues alive, which could dramatically impact the field of regenerative medicine. Vascular toolbox Bellan’s lab is hoping these...

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Researchers seek answers to cancer, diabetic wounds in controlling gene networks

Mar. 27, 2015—Behind the pathology for a variety of painful and deadly diseases lie genes that aren’t doing their jobs. They may be blocking the healing process for foot wounds in diabetic patients or contributing to cancer by interfering with the dying off of mutated or damaged cells. Kelsey Beavers, a Vanderbilt University Ph.D. candidate in interdisciplinary...

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Duvall to receive 2015 Society for Biomaterials Young Investigator Award for regenerative medicine research

Jan. 22, 2015—Assistant Professor of Biomedical Engineering Craig L. Duvall has received a Society for Biomaterials 2015 Young Investigator Award for his achievements in the field of biomaterials research within 10 years of receiving his doctorate. The award will be presented at the Society’s 2015 annual meeting in Charlotte, N.C., April 15-18. His manuscript, “Conjugation of Palmitic...

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Duvall receives NSF Early Career award

Aug. 28, 2014—Assistant Professor of Biomedical Engineering Craig L. Duvall has received a National Science Foundation Faculty Early Career Development grant. The five-year, $500,000 grant – Polythioketal Hydrogel For SiRNA-Enhanced Regenerative Cell Therapies – will allow Duvall to continue research on advanced drug delivery systems designed to enhance the performance of stem cell therapies for use in...

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