NIH
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Study links Celebrex, heart valve calcification after earlier research declared drug safe
A well-known, four-year study found popular arthritis drug Celebrex no more dangerous for the heart than older drugs in its same classification – commonly called NSAIDs. Now, a big-data analysis of patient records at Vanderbilt University has found a link specifically between Celebrex and heart valve calcification. W. David… Read MoreFeb. 22, 2019
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First step toward model brain: turning iPSCs into working blood-brain barrier
Vanderbilt University engineering researchers took a major step toward building a “brain in a dish:” They cultured induced pluripotent stem cells into a successful three-dimensional blood-brain barrier model. The future of drug testing and disease research lies in creating organoids, or models of human organs, to determine efficacy and potency… Read MoreFeb. 21, 2019
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Nanoparticle targets tumor-infiltrating immune cells, flips switch telling them to fight
New research builds on Nobel-winning immune checkpoint blockade work Immunotherapy’s promise in the fight against cancer drew international attention after two scientists won a Nobel Prize this year for unleashing the ability of the immune system to eliminate tumor cells. But their approach, which keeps cancer cells from shutting off… Read MoreJan. 21, 2019
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VISE affiliates awarded $2.5 million NIH grant for continued epilepsy research
A team of Vanderbilt University engineers and surgeons has received a five-year, $2.5 million National Institutes of Health R01 grant to continue research into epilepsy-related seizures and brain networks. Victoria Morgan, associate professor of radiology and radiological sciences, is the principal investigator. Bennett Landman, associate professor of electrical engineering and… Read MoreNov. 17, 2018
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Make science and medical research passionate and personal, expert urges
America as a whole is losing its passion for science, a trend that jeopardizes biomedical advancements to cure disease, ease suffering, and improve lives, the head of a top academic association said Wednesday. “If we want science and medical innovation to once again define what America wants to be then… Read MoreMar. 28, 2018
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Shining a light on the nervous system to thwart disease
E. Duco Jansen, professor of biomedical engineering at Vanderbilt, and two other Vanderbilt professors developed the underlying infrared nerve modulation technology for the research into treating disease with light. (Vanderbilt University/Daniel Dubois) Vanderbilt University researchers are teaming with peers from two other universities to develop ways to fight disease with… Read MoreNov. 16, 2017
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NIH-funded collaboration to develop steerable robotic needles for lung biopsies
What started as graduate school research with steerable needles in blocks of gelatin could help pulmonologists more accurately reach sites in the peripheral lung to biopsy them. A collaboration between that doctoral student – now Associate Professor of Mechanical Engineering Robert Webster; Dr. Fabien Maldonado a pulmonologist at Vanderbilt University… Read MoreNov. 8, 2017
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VISE team wins $1.4 million NIH grant to reboot robotic surgery system
From the left, Associate Professor Robert Webster III, Dr. S. Duke Herrell and Harvey Branscomb Professor Michael Miga, lead a VISE team developing an image guidance interface for robotic surgery systems. (Anne Rayner/Vanderbilt) A Vanderbilt Institute for Surgery and Engineering (VISE) team is developing an image guidance interface for the… Read MoreOct. 17, 2017
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New tissue-chip research to assess efficacy of novel epilepsy drugs
NeuroVascular Unit and its perfusion controller, left, and the cardiac I-Wire system, right. (VIIBRE / Vanderbilt) An interdisciplinary team of Vanderbilt University researchers led by John Wikswo, A.B. Learned Professor of Living State Physics and Gordon A. Cain University Professor, has received a two-year, $2 million federal grant to develop an “organ-on-chip”… Read MoreSep. 22, 2017
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Six profs attract National Institutes of Health grants for wide-ranging research
David Merryman is one of six engineering professors who earned R01 grants for their research. (Vanderbilt University) Five biomedical engineering professors and an electrical engineering and computer science professor are celebrating news about newly approved or resubmitted Research Project Grants (R01) from the Nationals Institutes of Health. Read MoreJul. 12, 2016